HEALTH & CARE

Best Flea and Tick Medicine for Dogs: Effective and Long Lasting Protection Against Itching and Diseases

Woman applies tick medicine to fluffy dog.
Wyatt Robinson
Written by Wyatt Robinson

Spring and summer are the peak time for fleas and ticks. These insects like to live and breed on the coats of our beloved pet dogs. Pets usually get fleas and ticks when staying outside or through contact with other dogs. Once your pet gets infected with these insects, they also bring the colony home causing them to spread to your furniture and bedding.

Fleas and ticks can cause itching and skin conditions. They also harbor diseases which can be harmful to your family. This is why finding the best flea and tick medicine for dogs is important. It does not only protect your pet but your family too.

Image showing a big brown dog sitting outside on the grass on a shiny day

Flea and tick medicine for pets is an effective over-the-counter solution for eliminating and preventing the insects from infesting your dog. A good flea and tick remedy should not only be effective but easy to use.

There are many different types of medicine like topical, oral drops, pet shampoos, powder and collars. When looking for a flea and tick solution, it is important to consider your lifestyle and your dog’s age so that you can choose a prevention type that is most effective.

Product NameApplication TypeDosageBest UsePrice
PetArmorPro AdvancedTopicalOnce A MonthFor dogs 45-88.9 lbs and puppies older than 8 weeksCheck price on Amazon
Sentry Fiproguard Plus for DogsSqueeze-OnOnce A MonthFor dogs 45-88 lbs and puppies older than 8 weeksCheck price on Amazon
Frontline Plus Flea and Tick ControlSqueeze-OnOnce A MonthDogs 45 to 88 lbsCheck price on Amazon
Bayer K9 Advantix IITopicalOnce A MonthDogs over 55 lbs and puppies over 7 weeks oldCheck price on Amazon
Pronyl OTC MaxSqueeze-OnOnce A MonthDogs 45-88 lbs and over 12 weeks oldCheck price on Amazon
Bayer Advantage IITopicalOnce A MonthDogs 3-10 lbs and puppies over 7 weeks oldCheck price on Amazon
PetLock Plus Dog Flea TreatmentSqueeze-OnOnce A MonthFor dogs 45-88 lbs and puppies older than 8 weeksCheck price on Amazon
Terra Pet Naturals Topical TreatmentTopical DropsEvery 2-5 daysAll dog breed and sizesCheck price on Amazon

Things To Consider Before Buying

Because there are different types of flea and tick medicine for dogs available, it can be very difficult to choose the best one for your pet. There are simply too many brands and types of solutions, making the selection process confusing. The fact is, not all flea and tick medicine offer the same kind of protection. Understanding the different features of each solution and considering your lifestyle can help you choose the best flea and tick medicine for your dogs.

Usage

There are many different solutions to tick and flea infestations. You have collars, sprays, powder, squeeze-on tubes, topical treatment and shampoos. To find out what the best type of solution is best for you and your dog, take a look at your pet’s behavior. Some pet do not have time to bathe their dogs regularly, so in this case a pet shampoo will be ineffective.

Image presenting a dog bathing outside in the sun

There are also dogs that like to go swimming and a waterproof flea and tick medicine is a good choice for this type of behavior. If you’re busy and prefer a solution that does not require constant application, look into topical medications that can be applied once a month. Knowing how your pet behaves and your lifestyle can help you determine a good type of flea and tick solution.

Function

Function also has a big impact on your pet and family. Manufactures of flea and pet medicine for dogs design their products in different ways. There are medications intended to kill and prevent future infestation while there are products that only kill the existing parasites.

Image showing a brown dog scratching

In this instance, you need to take a look at your lifestyle. If your pet spends lots of time outdoors or has a lot of contact with other dogs, medication that eliminates and repels ticks and fleas is more efficient. This is because without consistent protection, your dog can become a buffet for the insects which can lead to anemia and other diseases.

Effectiveness

It can be overwhelming but there are hundreds of different tick and flea species. Some of the most common species are the black legged tick, American dog tick and brown dog tick. It can be intimidating to look for medicine that is designed for specific species of flea and tick and in this case it is always better and safer to go with medicine that is labeled as «broad spectrum». This means that it is effective for most species of fleas and ticks so you are ensured of a wider range of effectiveness.

Woman applies tick medicine to a dog.

The type of active ingredient can also impact the effectiveness of the medication. Some of the most common ingredient in flea and tick medication includes Fipronil for example is a broad-spectrum insecticide that is spread by the oils on the dog’s coat, killing fleas and ticks within 24 hours.

Arylheterocycles works by blocking the passage of chlorine through cells of ticks and fleas nervous system causing paralysis. Learning about the different types of active ingredients used by flea and tick medicine can help you control and repel the insects more effectively.

Intended for Dogs or Cats?

There are many medications that can be taken safely by both dogs and cats. This is great especially if you have both pets living under one roof. Buying one type of medicine can help you save money. However, not all flea and tick medicine can be given to cats and dogs alike. When looking for a good flea and tick solution for your dog, buy medicine that is intended for dog use.

Image showing a fluffy cat looking at the camera

This is because dogs and cats require different types of active ingredients or have different dosage. There are also some ingredients that are fatal to cats and vice versa. Read the label before purchasing to make sure that the product you buy is intended to kill or repel ticks and fleas in dogs.

Age and Weight of Dog

Most manufacturers make flea and tick medication designed for a specific weight class. For example, there are medicines that are for small dogs, medium dogs and large dog breeds. Before buying any flea and tick solution, weigh your dog first. The weight of your dog is important because giving medication intended for large dogs to small dogs can be fatal. This is mainly due to the dosage in the medication.

Image showing a big brown dog looking at the moutain landscape

Anti flea and tick medication is also unsafe for puppies younger than 7 weeks old. Always find a product that is not only weight appropriate but also age appropriate for your pet’s safety.

Do not buy medicine that does not meet your dog’s individual needs. For example, don’t buy a flea and tick medicine that is waterproof if your dog only «swims» in the bathtub. Always go for a product that offers multiple protection. Medicine that kills and repels fleas and ticks is always better than a product that only kills fleas.

Best Products on Today’s Market

One of the best ways to find a good flea and tick medicine for dogs is by doing a little research on the internet first. This is a good way not only to find good products but also to find reviews of past users and to learn about their experience with the product. Comparing and studying different products can help you determine the best solution for your dog.

PetArmorPro Advanced PetArmorPro Advanced

Price: approx. $19.95

Application Type: topical

Dosage: once a month

Features: kills and repels fleas, ticks and chewing lice, waterproof

Best Used By: dogs 45-88.9 lbs and puppies over 8 weeks old

Description: The PetArmorPro Advanced kills and repels ticks, fleas, lice and mosquitoes. This is a quick acting and long lasting solution against pesky pets that can harm pets and family members. This is a great product for dog owners who live in places that do not only have ticks, fleas and lice but mosquitoes too.

This is a waterproof topical application that is easy to use and waterproof. The superior action of the product starts to repel insects in 10 minutes. Aside from this, it also helps to control sarcoptic mange infestations. When used as directed it can help to eliminate fleas, ticks, mosquitoes, lice and sarcoptic mange mites.

The product is easy to use. Simply empty the whole contents of a tube between the shoulder blades of your pet once a month. This will give you protection from adult fleas up to 3 months. To ensure protection and control over ticks, apply one a month. Enjoy the sight of mosquitoes flying over your dogs but never landing. This is a good solution for large dogs who like to go swimming or like to stay outside; as well as a convenient and a good choice for busy pet owners.

Pros:

  • Convenient to use
  • Affordable
  • Kills and repels ticks and fleas

Cons:

  • Can cause flea allergy dermatitis to susceptible puppies

Related: Your dog’s coat will look great with the GoPets Dematting Comb. Clear up matt and tangles with this multi-toothed comb for a well-groomed look.

Check the price on Amazon

Sentry Fiproguard Plus for Dogs Sentry Fiproguard Plus for Dogs

Price: approx. $44.75

Application Type: squeeze-on

Dosage: once a month

Features: waterproof, kills flea eggs and flea larvae, can be used by pregnant or lactating female dogs

Best Used By: dogs 45-88 lbs and puppies older than 8 weeks

Description: The Sentry Fiproguard Plus for Dogs works by breaking the flea life cycle. Once applied it kills flea eggs and flea larvae for up to 12 weeks and prevents infestation up to 4 weeks. It also kills adult fleas which could be the source of your dog’s flea allergy dermatitis. Aside from this, it also kills fleas that can cause Lyme disease.

This waterproof flea and tick solution contains vet-recommended fipronil that kills fleas, flea larvae, ticks and chewing lice. It is a fast-acting formula designed to protect your dog against pesky pests. This product is designed for dogs 8 weeks of age and over, weighing between 45 to 88 pounds. It is also safe to use by female dogs that are breeding, pregnant or lactating.

This easy to use squeeze-on formula can control and prevent infestation for 30 days, making it a good choice for busy dog owners who are also looking for something that is convenient. Fiproguard Plus is also a good choice for active dogs that like to stay outdoors and swim in rivers or lakes.

Some pet owners reported that the product smells bad and their dogs noticing quickly causing the dogs to try to escape and try to wipe off the products on the couch or carpet.

Pros:

  • Waterproof
  • Long lasting and easy to use
  • Can be used by female dogs that are breeding, lactating or pregant

Cons:

  • Bad smell
  • Does not repel mosquitoes (only ticks and fleas)
  • Expensive

Related: This Flea and Tick Control Collar Clip from La Relief offers 6 months insect protection. It contains a strong blend of 100% natural aromatherapy oils for holistic protection against mosquitoes, gnats, ticks, fleas and lice.

Check the price on Amazon

Frontline Plus Flea and Tick Control Frontline Plus Flea and Tick Control

Price: approx. $34.19

Application Type: squeeze-on

Dosage: once a month

Features: easy 3-step application process, waterproof, tick-relief for up to 3 months

Best Used By: dogs 45 to 88 lbs

Description: The Frontline Plus Flea and Tick Control is a monthly squeeze-on product that is effective up to 1 month. It kills 100% of adult fleas on your dog within 18 hours and 100% of all ticks within 48 hours. The product contains S-methoprene, an insect growth regulator that kills flea eggs and larvae. It is effective against common flea and tick species including brown dog tick, the American dog tick, the lone-star tick and the deer tick (major carrier of Lyme disease).

The product is waterproof for 30 days and is very easy to apply. Just follow the steps directed on the product and you and your dog can enjoy a month free of pests and insects. This vet-recommended product works by killing flea eggs and flea larvae as well as eliminating adult fleas and ticks. It is also effective against chewing lice.

Use monthly to completely break the flea life cycle. It also prevents the development of all flea stages for up to 3 months making it effective as a flea repellent especially if your dog has frequent contact with other dogs. A once a month application is also recommended to kill and repel ticks and control chewing lice.

Pros:

  • Easy application process
  • Breaks flea life cycle
  • Kills and repels fleas and ticks

Cons:

  • Expensive

Related: Relieve itchy and dry skin with Pet MD Oatmeal Dog Shampoo. It provides safe and anti-itch treatment that relieves skin irritation and promotes healing for sensitive and dry itchy skin.

Check the price on Amazon

Bayer K9 Advantix II Bayer K9 Advantix II

Price: approx. $60.49

Application Type: topical

Dosage: once a month

Features: ills fleas, ticks and mosquitoes through contact, easy to apply, waterproof

Best Used By: dogs over 55 lbs and puppies over 7 weeks old

Description: The Bayer K9 Advantix II kills adult fleas, eggs and larvae. Biting fleas can be a nuisance for your dogs and if left unchecked can cause flea allergy dermatitis, skin infection, tapeworm and even anemia. This topical solution lets you stop fleas before they become a problem. A monthly application of the product stops fleas from biting in just 5 minutes. It can kill 98 t 100% of fleas in 12 hours and work for up to a month.

The product works by killing fleas. Adult fleas cannot lay eggs and since there are no eggs, there are no larvae, thereby breaking the flea life cycle. This is a powerful medication that can also kill and repel ticks before they can attach to your dog. Advantix II is also effective in repelling mosquitoes. If applied before flea and tick season starts, it can save your dog from uncomfortable spring and summer seasons. Use it all year round to prevent fleas from over-wintering in your home and feasting on your dog during the summer season.

Advantix II is designed to work on dogs over 55 lbs but is gentle enough to use on puppies over 7 weeks old. This flea control system remains effective even when your dog is bathing or swimming. Use regularly not only to control fleas but also to prevent tick bites that can cause Lyme disease or Rocky Mountain spotted fever. It is also effective against repelling mosquitoes that can cause heartworm or West Nile virus to your dog.

Pros:

  • Effective in killing and repelling fleas, ticks and mosquitoes
  • Easy to use
  • Waterproof

Cons:

  • Very expensive

Related: Reduce dental plaque, bacteria and tartar buildup with Spray Me: Doggy Dental Spray from TruDog. Freshen breath and improve dental health in your dog without brushing and fussing.

Check the price on Amazon

Pronyl Otc Max Flea Tick for Dogs Pronyl Otc Max Flea Tick for Dogs

Price: approx. $9.99 to $21.01

Application Type: squeeze-on

Dosage: once a month

Features: waterproof, 5-year shelf-life, starts killing in 1 hour

Best Used By: dogs 45-88 lbs and over 12 weeks old

Description: If you want fast action, try Pronyl Otc Max Flea Tick for Dogs. This product starts killing ticks and fleas in as little as 1 hour for fast relief from itching and flea allergy dermatitis. It contains vet-recommended fipronil plus a second active ingredient (cyphenothrin) to effectively safeguard your dog against fleas, ticks and chewing lice.

This product works fast and stops re-infestation in a sustained release formula developed to be long-lasting and control of fleas and ticks. It is effective against brown ticks, American and lone star dog ticks for up to 4 weeks. Independent clinical studies show that Pronyl OTC Max kills fleas and ticks at a faster rate compared to other products while maintaining efficacy throughout the month.

Give your dog one month protection against itching and skin disease while protecting your family against Lyme disease. This product is a good choice for busy dog owners who want a product that is easy to apply. Use this product monthly so that your dog can enjoy flea and tick free months with you and your family reducing exposure to flea allergy dermatitis, anemia and diseases spread by fleas.

Pros:

  • Fast acting
  • Affordable
  • Effective combination of ingredients

Cons:

  • Active ingredients can be toxic to humans

Related: Control fleas without harmful ingredients and chemicals with the Safari Flea Comb. Its double row of teeth is effective in removing fleas and debris from your dog’s coat. It is also effective in grooming your dog.

Check the price on Amazon

Bayer Advantage II Topical Flea Treatment Bayer Advantage II Topical Flea Treatment

Price: approx. $37.29

Application Type: topical

Dosage: once a month

Features: kills fleas on contact, stops the flea life cycle, easy to apply

Best Used By: dogs 3-10 lbs and puppies over 7 weeks old

Description: Prevent flea and lice infestation in dogs with the Bayer Advantage II Topical Flea Treatment. This once a month treatment for fleas and lice is waterproof, making it a good choice for dogs that love to swim and bathe. The product contains active ingredients like Imidacloprid, a topical insecticide that kills adult fleas and larvae and Pyriproxyfen, an insect growth regulator that inhibits the hatching and development of flea eggs.

Regular use of the product does not only kill and repel fleas; it is also effective against lice helping you to end the misery of your dog against these pests. Advantage II is effective even without biting. Once fleas and lice make contact with the treated coat of your dog, the active ingredients work within 12 hours to kill and reduce infestation. It also works up to 1 month to give your dog lasting protection.

Use this product regularly because fleas don’t just make your dog itchy. They will keep biting and making your dog uncomfortable. If fleas are ingested, they can also cause tapeworms which can be fatal for your dogs. Fleas can be brought inside your home unknowingly when they spend time outdoors or through contact with other infected dogs. Monthly use reduces your dog’s risk of flea and lice infestation since it kills on contact including adult and larvae fleas.

Pros:

  • Easy to use
  • Good blend of active ingredients
  • Kills fleas and lice

Cons:

  • Does not kill or repel ticks and mosquitoes
  • Expensive

Related: Treat your dog’s ear mites with Lively Pets Ultra-Otic Advanced. It is also effective treatment against yeast and bacteria for relief against ear itch, head shaking, discharge and odor.

Check the price on Amazon

PetLock Plus Dog Flea Treatment PetLock Plus Dog Flea Treatment

Price: approx. $29.99

Application Type: squeeze on

Dosage: once a month

Features: waterproof, contains fipronil and s-methoprene, controls sacropic mange mite infestation

Best Used By: dogs 45-88 lbs and puppies older than 8 weeks

Description: Kill fleas, flea eggs and larvae with the PetLock Plus Dog Flea Treatment. It is also effective against all stages of ticks including those that transmit Lyme disease. Aside from this, it also aids in controlling sarcoptic mange mite infestation that is caused by the burrowing mite that digs through your dog’s skin causing intense itching and an allergic reaction against the mite and crusting that can quickly become infected.

A once-monthly application for your dog means a continued protection not only against itching but also by the diseases caused by these insects. The active ingredients of the product are fiponril a well known insecticide that kills fleas and ticks on contact.

It also contains s-methoprene, a flea and tick control medication that prevents flea pupae and larvae from growing into breeding adults. It also works by killing eggs and stopping them from hatching. Enjoy this flea and tick control benefits for dogs weighing 45-88 lbs and puppies older than 8 weeks.

The combination of these ingredients makes the product a good flea and pet control medication. The product is fast acting, waterproof and long lasting providing your dog and family protection against fleas, ticks and chewing lice.

Pros:

  • Affordable
  • Good combination active ingredients
  • Stops flea life cycle

Cons:

  • Does not repel mosquitoes

Related: The Beloved Pets Flea&Tick Collar controls fleas and ticks in dogs and puppies. It is safe and non-toxic that protects the entire body of your dog for at least 4 months.

Check the price on Amazon

Terra Pet Naturals 100% Natural Flea and Tick Repellent 100% Natural Flea and Tick Repellent

Price: approx. $18.99

Application Type: topical drops

Dosage: every 2-5 days

Features: all-natural ingredients, repels ticks and fleas, eco-friendly, non-toxic

Best Used By: all dog breeds and sizes

Description: For dog owners looking for a flea and tick repellent that is all natural, the 100% Natural Flea and Tick Repellent by Terra Pet Naturals is a good choice. It contains organic sunflower oil, rose geranium oil, lemongrass oil, eucalyptus oil, lavender oil, citronella oil, clove oil, peppermint oil, cedar wood oil, neem oil, tea tree oil, white thyme oil and castor oil to form a blend of essential oils that naturally ticks, fleas, mosquitoes and other insects from infesting your dog.

The product is completely safe, non-toxic, non-toxic, chemical-free and pesticide-free, making it a perfect choice for dog owners looking for something that is not only safe for their pets but also safe for the environment and for humans too. When you are using this product, you don’t need to worry about touching your pet while the product dries because your dog is completely safe to touch right after application.

While this product is a natural flea, tick and mosquito repelling product, it does not kill the insects that are already infesting your dog. Therefore, it is recommended that dog owners use another product to kill and eliminate ticks, lice, fleas and other insects from your dog before applying the product. It is also recommended by the manufacturer to spray the product in addition to the drops in areas that are high concentration of ticks and fleas.

Pros:

  • All natural ingredients
  • Pet, planet and human safe
  • Easy to apply and affordable

Cons:

  • Does not kill existing fleas or ticks or their eggs and larvae
  • Need to apply 2-5 times a week to be effective

Related: Remove flea eggs and dirt naturally with the Petio Basics Flea Comb. The tightly spaced pins will put your dog out of its misery by stripping away fleas and their eggs from your dog’s undercoat.

Check the price on Amazon

Wrap Up

It is easy to be overwhelmed what with the numerous types and kinds of flea and tick medications available in today’s market. To ensure that you are buying the best product for your dog, examine your lifestyle and your dog’s needs. It is also recommended that dog owners check with their veterinarian before using a flea and tick medicine to prevent compilations.

Certain products could contain chemicals or ingredients your dog is allergic to or it could exacerbate serious conditions. Dog owners only want the best for their dogs. The best flea and tick solution is something that is convenient, affordable and safe for both pet and owner.

Image showing a side picture of a big dog

Have you tried any of the products listed above? What do you think is the best type of flea and tick solution? Do you think that there are other products that are more effective than the ones we have reviewed? Tell us what you think by commenting below.

About the author
Wyatt Robinson
Wyatt Robinson

Wyatt Robinson had a great 25-years career as a veterinarian in United Kingdom. He used to be a member of British Veterinary Association and worked in 3 pet hospitals in London and Manchester. He is shining when he sees his pets healthy and full of energy and it is his duty to help other dog owners to keep their best friends full of life.

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